Günther Lab

Microbial EVs as novel avenues for host-microbe interaction

Our research group is dedicated to exploring the role of extracellular vesicles (EVs) in host-microbe communication and inter-organ cross-talk, with a particular focus on their impact in immune-mediated inflammatory disorders and cancer. We investigate how EVs, especially those derived from bacteria, contribute to disease processes and how they can be harnessed for therapeutic applications. Our central aim is to bridge disciplines such as gastroenterology, neurology, microbiology, and stem cell biology to understand the complex interactions between EVs and their hosts, ultimately translating these findings into novel clinical treatments.

Through our multidisciplinary approach, we aim to unlock the full potential of EVs as both biomarkers for disease and as therapeutic agents. By investigating how EVs can modulate inter-organ communication and immune responses, we hope to develop new strategies for treating a range of diseases, ultimately paving the way for clinical applications that can improve patient outcomes.

Principal Investigator:

Prof. Dr. rer. nat. Claudia Günther

Professorship for Gastrointestinal Pathophysiology